Fellows



Oliver Baretella, M.D., Ph.D.

Dr. Baretella is a graduate of the University of Zurich School of Medicine. Prior to completing his medical doctorate at the University of Zürich he studied the role of estrogen receptors and endothelial factors in the regulation of vascular tone. Dr. Baretella's research is focussed on endothelium-dependent pathways regulating vascular disease and inflammation in obesity. Dr. Baretella holds a Ph.D. from the University of Hong Kong and is the recipient of post-doctoral fellowships from the Swiss National Science Foundation (SNSF).


SELECTED PUBLICATIONS

Paradoxical lack of increase in endothelin-1 levels in obese mice - possible role of endothelin-B receptors
O. Baretella, S.K. Chung, A. Xu, P.M. Vanhoutte
Acta Pharmacol Sin 38, 1699-1700, 2017



Endothelial overexpression of endothelin-1 modulates aortic, carotid, iliac and renal arterial responses in obese mice
O. Baretella, S.K. Chung, A. Xu, P.M. Vanhoutte
Acta Pharmacol Sin 38, 498-512, 2017



Endothelium-dependent contractions: prostacyclin and endothelin-1, partners in crime?
O. Baretella, P. M. Vanhoutte
Adv Pharmacol 77, 177-208, 2016



Obesity and heterozygous endothelial overexpression of prepro-endothelin-1
modulate responsiveness of mouse main and segmental renal arteries to vasoconstrictor agents

O. Baretella, S.K. Chung, M. Barton, A. Xu, P.M. Vanhoutte
Life Sci 118, 206-212, 2014


Prostaglandin I2 receptor blockade contracts rat renal arteries and facilitates endothelium-dependent contractions
O. Baretella, Y. Xu, P.M. Vanhoutte
Hypertension 64, A335, 2014


Role of IP receptors in renal basal arterial tone and endothelium-dependent contractions
O. Baretella, Y. Xu, P.M. Vanhoutte
J HK Coll Cardiol 22, 51, 2014


Acidosis prevents and alkalosis augments endothelium-dependent contractions in mouse arteries
O. Baretella, Y. Xu, P.M. Vanhoutte
Pflugers Arch 466, 295-305, 2014


Development of osteoarthritis-.ike changes in transgenic endothelin-1 over-expressed mice
C. Wen, L.C. Pei, O. Baretella, S. K. Chung, A. Xu, C.H Yan, K.Y. Chiu, W. W. Lu
Life Sci 93, e1-e2, 2013


Heterozygous endothelial endothelin-1 overexpression potentiates endothelium-dependent
contractions in the carotid artery of obese mice
O. Baretella, S. K. Chung, A. Xu, P. M. Vanhoutte
Hypertension 62, A643, 2013



Heterozygous overexpression of preproendothelin-1 in endothelial cells enhances
thromboxane-prostanoid receptor-induced contractions in the renal artery of obese mice

O. Baretella, A. Xu, S. K. Chung, P. M. Vanhoutte
Life Sci 93, e3, 2013


Contractions to endogenous and exogenous endothelin-1 in
segmental renal arteries of the mouse: up-regulation by obesity

O. Baretella, A. Xu, S. K. Chung, P. M. Vanhoutte
Life Sci 2013


Improved relaxation to acetylcholine in murine carotid arteries with
heterozygous overexpression of preproendothelin-1 in the endothelium
O. Baretella, A. Xu, S. K. Chung, P. M. Vanhoutte
Life Sci 2013


Reduction of contractions to phenylephrine by L-NAME in the carotid artery
of mice with endothelial overexpression of endothelin-1

O. Baretella, F.Y. Li, S.K. Chung, P.M. Vanhoutte
FASEB J 26, 1129, 2012


Obesity and risk of vascular disease: Importance of endothelium-dependent vasoconstriction

M. Barton, O. Baretella, M.R. Meyer
Br J Pharmacol 165, 591-602, 2011


Dilation of epicardial coronary arteries by the G protein-coupled
estrogen receptor agonists G-1 and ICI 182,780

M.R. Meyer, O. Baretella, E.R. Prossnitz, M. Barton
Pharmacology 86, 58-64, 2010


Role of nitric oxide and endothelin in coronary artery function
mediated by the novel membrane estrogen receptor GPER

M. R. Meyer,
O. Baretella, E. R. Prossnitz, M. Barton
Hypertension 54, e81, 2009



Activation of GPER inhibits contraction to endothelin-1 and
causes NO-dependent relaxation of coronary arteries

O. Baretella, M.R. Meyer, E.R. Prossnitz, M. Barton
The Physiologist 52 (6): 289, 2009


Role of nitric oxide and endothelin in coronary artery function
mediated by the novel membrane estrogen receptor GPER

M.R. Meyer,
O. Baretella, E.R. Prossnitz, M. Barton
Hypertension 54, e81, 2009